Web Designer Salt Lake has published an excellent article comparing Hero Framework to Wordpress in terms of publishing, plugins, eCommerce, and search engine optimization. I'll give you a hint: Hero wins in all categories!
The way Hero handles different sets of data is a lot more intuitive and logical. Hero comes with great features for customization out of the box such as separate web blogs, custom fields, forms etc. These can take an hours to set up in Wordpress can be done in minutes in Hero. Therefore you can get the functionality and layout you need done in no time at all with a system like Hero. Along these lines, the template system for Hero is also extremely simple to use. The designer can simply call content and variables into the site and place them where they are needed. Entire sites can be up and running in a few days, instead of weeks!
Read the full review: Alternatives to Wordpress: Hero Framework. 5 Reasons to consider Hero.